Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27490462 | 0.85 | TRPM5 (0.39) | TRPM5HTR2CHTR2ASCN9A | |
| Ethoxycarbonyl Group SCHEMBL27492236 | 0.79 | CREBBP (0.42) | CREBBPTRPM5TUBB4ATUBBTUBA3C | |
| Ethoxycarbonyl Group SCHEMBL27474750 | 0.74 | CNR1 (0.48) | CREBBPTRPM5TUBB4ATUBBTUBA3C | |
| SCHEMBL3596244 | 0.71 | LMNA (0.60) | TRPM5HTR2CHTR2AALDH1A1MEN1 | |
| SCHEMBL27490854 | 0.71 | TRPM5 (0.38) | CREBBPTRPM5L3MBTL1CNR1MCL1 | |
| SCHEMBL399775 | 0.71 | MAPT (0.58) | CREBBPTRPM5TUBB4ATUBBTUBA3C | |
| SCHEMBL13261931 | 0.70 | ALDH1A1 (0.54) | CREBBPHTR2CL3MBTL1HTR2AALDH1A1 | |
| SCHEMBL7957934 | 0.70 | F10 (0.53) | L3MBTL1ALDH1A1MEN1KMT2APSEN1 | |
| Ethoxycarbonyl Group SCHEMBL27474221 | 0.69 | MCL1 (0.42) | CNR1MCL1FABP4 | |
| SCHEMBL8959711 | 0.68 | HTR2C (0.45) | TRPM5HTR2CHTR2AALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1161334-A | Novel substd. guanidine derivs., process for prodn. thereof, and pharmaceutical uses thereof | SUMITOMO PHARMA (JP) | 1997-10-08 | — | — | CN | disclosed |