Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.68 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27473109 | 0.92 | LIMK1 (0.57) | IKBKBLIMK1MAPTALDH1A1HPGD | |
| SCHEMBL6219257 | 0.88 | KMT2A (0.58) | IKBKBLIMK1MAPTALDH1A1HPGD | |
| SCHEMBL6218572 | 0.85 | ALDH1A1 (0.58) | IKBKBLIMK1MAPTALDH1A1HPGD | |
| SCHEMBL6216835 | 0.85 | KMT2A (0.80) | IKBKBLIMK1MAPTALDH1A1HPGD | |
| SCHEMBL4193885 | 0.84 | IKBKB (0.72) | IKBKBLIMK1MAPTALDH1A1HPGD | |
| SCHEMBL4199055 | 0.84 | LIMK1 (0.83) | IKBKBLIMK1MAPTALDH1A1HPGD | |
| SCHEMBL4188967 | 0.81 | LIMK1 (0.69) | IKBKBLIMK1MAPTALDH1A1HPGD | |
| SCHEMBL4463870 | 0.81 | PTGS2 (0.72) | IKBKBLIMK1MAPTALDH1A1HPGD | |
| SCHEMBL4193124 | 0.81 | LIMK1 (0.69) | IKBKBLIMK1MAPTALDH1A1HPGD | |
| SCHEMBL4197344 | 0.81 | LIMK1 (0.69) | IKBKBLIMK1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177848-C | Bicyclic heteroaromatic compounds useful as LH agonists | ��˹��ŵ�� | 2004-12-01 | — | — | CN | disclosed |
| CN-1349535-A | Bicyclic heteroaromatic compounds useful as LH agonists | AKZO NOBEL NV (NL) | 2002-05-15 | — | — | CN | disclosed |