Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714067 | 0.79 | KDM4E (0.67) | HPGDKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL16224674 | 0.76 | FGFR1 (0.37) | HPGDKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL4983073 | 0.76 | KDM4E (0.47) | HPGDKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL6628730 | 0.76 | ALDH1A1 (0.61) | HPGDKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL31270892 | 0.76 | ALDH1A1 (0.61) | HPGDKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL27972665 | 0.75 | CYP11B1 (0.41) | HPGDKDM4EHSD17B10ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL29913261 | 0.74 | ALDH1A1 (0.59) | HPGDKDM4EHSD17B10ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL27157845 | 0.74 | ALDH1A1 (0.59) | HPGDKDM4EHSD17B10ALDH1A1MEN1 | |
| SCHEMBL20099158 | 0.74 | IDO1 (0.50) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL29093412 | 0.73 | KDM4E (0.48) | HPGDKDM4EHSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1173931-C | Acenaphthene derivative compound and its application | 宋 航 | 2004-11-03 | — | — | CN | disclosed |
| CN-1394849-A | Acenaphthene derivative compound and its application | SONG HANG (CN) | 2003-02-05 | — | — | CN | disclosed |