Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270892 | 0.80 | ALDH1A1 (0.61) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL6628730 | 0.80 | ALDH1A1 (0.61) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL27474385 | 0.79 | HPGD (0.57) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL27157845 | 0.78 | ALDH1A1 (0.59) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL29913261 | 0.78 | ALDH1A1 (0.59) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL20021100 | 0.78 | HPGD (0.44) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL8622634 | 0.77 | LMNA (0.70) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL6155294 | 0.76 | LMNA (0.60) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL8622181 | 0.76 | ALDH1A1 (1.00) | KDM4EHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL4981716 | 0.76 | ALDH1A1 (0.56) | KDM4EHPGDHSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847006-A | Therapeutic guanidines | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0746316-A4 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE INC (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0746316-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995014467-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1995-06-01 | — | — | WO | disclosed |