Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27474142 | 0.98 | KMT2A (0.43) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| SCHEMBL27707083 | 0.77 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| Hydrochloric Acid SCHEMBL9574607 | 0.76 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| Hydrochloric Acid SCHEMBL9574577 | 0.72 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| SCHEMBL27488987 | 0.72 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| SCHEMBL4252730 | 0.70 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| Bromide SCHEMBL28521427 | 0.70 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| SCHEMBL28784285 | 0.69 | PARP1 (0.45) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| Bromide SCHEMBL7626002 | 0.69 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1NPSR1LMNA | |
| Hydrochloric Acid SCHEMBL313570 | 0.69 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142778-C | Use of thiazolium compounds for preventing and reversing the formation of advanced glycosylation endproducts | ¶ | 2004-03-24 | — | — | CN | claimed |
| CN-106117055-B | A kind of synthetic method of vinyl tri carbonyl compound and the like | 安徽国星生物化学有限公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-108440370-A | Inhibitors of viral replication | 鲁汶天主教大学 | 2018-08-24 | — | — | CN | disclosed |
| CN-104024223-B | Inhibitors of viral replication | 鲁汶天主教大学 | 2018-07-24 | — | — | CN | disclosed |
| CN-100486573-C | Nitrocessed and nitrosylated cyclooxygenase-2 inhibitors, compositions, and uses thereof | NITROMED INC (US) | 2009-05-13 | — | — | CN | disclosed |
| CN-101426503-A | Compositions and methods of treatment for inhibiting kinase and/or HMG-COA reductase | PHARMIX CORP (US) | 2009-05-06 | — | — | CN | disclosed |
| CN-1434712-A | Nitrosated and nitrosylated cyclooxygenase-2 inhibitors compositions and methods of use | NITROMED INC (US) | 2003-08-06 | — | — | CN | disclosed |
| CN-1268937-A | Novel compound having effect of promoting neuron differentiation | NIPPON KAYAKU KK (JP) | 2000-10-04 | — | — | CN | disclosed |