Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252730 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KMT2ANPSR1MEN1LMNA | |
| Bromide SCHEMBL7626002 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KMT2ANPSR1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL313570 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KMT2ANPSR1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL9574577 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KMT2ANPSR1MEN1LMNA | |
| SCHEMBL27707083 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KMT2ANPSR1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL9574607 | 0.78 | ALDH1A1 (0.45) | ALDH1A1KMT2ANPSR1MEN1LMNA | |
| SCHEMBL6535191 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL3846709 | 0.75 | RAB9A (0.43) | ALDH1A1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL27627786 | 0.74 | TAAR1 (0.43) | ALDH1A1NPSR1CYP2D6CYP1A2SIGMAR1 | |
| SCHEMBL28784285 | 0.74 | PARP1 (0.45) | ALDH1A1KMT2ANPSR1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1255396-C | Carboxylic acid derivatives containing fused rings | EISAI CO LTD (JP) | 2006-05-10 | — | — | CN | disclosed |
| CN-1211361-C | Carboxylic acid derivatives containing fused rings | EISAI CO LTD (JP) | 2005-07-20 | — | — | CN | disclosed |
| CN-1548428-A | Carboxylic acid derivatives containing fused rings | ������������ʽ���� | 2004-11-24 | — | — | CN | disclosed |
| CN-1214042-A | Carboxylic acid derivatives containing fused rings | EISAI CO LTD (JP) | 1999-04-14 | — | — | CN | disclosed |