Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL2208140 | 0.94 | TSHR (0.39) | MEN1BLMKMT2ADPP4DPP8 | |
| Cadaverine Tartrate SCHEMBL6954617 | 0.94 | TSHR (0.39) | MEN1BLMKMT2ADPP4DPP8 | |
| Cadaverine Tartrate SCHEMBL4974761 | 0.90 | TSHR (0.46) | MEN1BLMKMT2ATSHR | |
| Proline SCHEMBL462226 | 0.87 | BLM (0.52) | MEN1BLMKMT2ADPP4DPP8 | |
| Proline SCHEMBL2939 | 0.87 | — | — | |
| Proline SCHEMBL462225 | 0.87 | BLM (0.52) | MEN1BLMKMT2ADPP4DPP8 | |
| Proline SCHEMBL13248912 | 0.87 | — | — | |
| Proline SCHEMBL10141181 | 0.87 | — | — | |
| D-Proline SCHEMBL21462052 | 0.87 | BLM (0.52) | MEN1BLMKMT2ADPP4DPP8 | |
| Proline SCHEMBL10141185 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111424060-B | Biological method for simultaneously preparing D-proline and L-1-pyrroline-5-carboxylic acid | 重庆邮电大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-1181054-C | Process for preparing D-proline | 东南大学 | 2004-12-22 | — | — | CN | disclosed |
| CN-1373125-A | Process for preparing D-proline | UNIV DONGNAN (CN) | 2002-10-09 | — | — | CN | disclosed |