Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 7/20 | 0.57 |
| ▸ | CTSC | P53634 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220110 | 0.94 | FKBP1A (0.53) | FKBP1ACTSCPIN1SLC6A2SLC6A4 | |
| SCHEMBL3674851 | 0.87 | FKBP1A (0.47) | FKBP1ACTSCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16586222 | 0.81 | FKBP1A (0.52) | FKBP1A | |
| SCHEMBL5016287 | 0.81 | FKBP1A (0.52) | FKBP1A | |
| SCHEMBL25756614 | 0.78 | FKBP1A (0.50) | FKBP1A | |
| SCHEMBL22861529 | 0.78 | FKBP1A (0.50) | FKBP1A | |
| SCHEMBL5017072 | 0.78 | HTR2C (0.47) | CTSCSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL1980413 | 0.78 | CTSC (0.55) | CTSCSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL3676417 | 0.78 | HTR2C (0.47) | CTSCSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL7222149 | 0.77 | FKBP1A (0.53) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1168443-C | Methods and compsns. for stimulating neurite growth using compounds with affinity for FKBP12 in combination with neurotrophic factors | ��̩��˹ҩ��ɷ�����˾ | 2004-09-29 | — | — | CN | claimed |
| CN-1239434-A | Methods and compsns. for stimulating neurite growth using compounds with affinity for FKBP12 in combination with neurotrophic factors | VERTED PHARMACEUTICALS INC (US) | 1999-12-22 | — | — | CN | claimed |