Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 16/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22861529 | 1.00 | FKBP1A (0.50) | FKBP1ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7222149 | 0.96 | FKBP1A (0.53) | FKBP1ALMNA | |
| SCHEMBL22861524 | 0.96 | LMNA (0.50) | FKBP1ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL21241510 | 0.96 | LMNA (0.50) | FKBP1ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL22861521 | 0.88 | HTR2C (0.47) | FKBP1AALDH1A1SMN1; SMN2 | |
| SCHEMBL21241284 | 0.88 | HTR2C (0.47) | FKBP1AALDH1A1SMN1; SMN2 | |
| SCHEMBL630942 | 0.83 | TSHR (0.61) | FKBP1AALDH1A1 | |
| SCHEMBL6727374 | 0.83 | TSHR (0.61) | FKBP1AALDH1A1 | |
| SCHEMBL28676037 | 0.82 | TSHR (0.60) | FKBP1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL630943 | 0.82 | TSHR (0.64) | FKBP1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3746440-B1 | PIPECOLIC ESTERS FOR INHIBITION OF THE PROTEASOME | UNIV TEXAS (US) | 2023-07-05 | — | — | EP | disclosed |