Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.66 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.60 |
| ▸ | CCR8 | P51685 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1519223 | 0.86 | MEN1 (0.69) | LTA4HS1PR5FAAH | |
| SCHEMBL3039936 | 0.85 | S1PR5 (0.81) | S1PR5 | |
| SCHEMBL27658773 | 0.85 | RAB9A (0.78) | LTA4HS1PR5HRH3SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2551741 | 0.85 | MEN1 (0.68) | LTA4HS1PR5FAAH | |
| SCHEMBL8791924 | 0.84 | CCR8 (0.81) | LTA4HHRH3CCR8SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1449444 | 0.84 | KMT2A (0.68) | LTA4HSMN1; SMN2ALDH1A1FAAHTP53 | |
| SCHEMBL6990156 | 0.84 | S1PR5 (0.67) | S1PR5HRH3 | |
| SCHEMBL22483727 | 0.84 | KCNH2 (0.59) | LTA4HS1PR5CHRM4 | |
| SCHEMBL24008595 | 0.84 | RAB9A (0.72) | LTA4HHRH3ALDH1A1FAAHNPC1 | |
| SCHEMBL5175763 | 0.83 | S1PR5 (0.69) | LTA4HS1PR5HRH3SMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147193-A | Insecticidal N-(substd. Arylmethyl)-4-[bis(substd. phenyl) methyl] piperidines | FMC CORP (US) | 1997-04-09 | — | — | CN | disclosed |