Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353607 | 0.91 | S1PR5 (0.58) | S1PR5MEN1KMT2ASIGMAR1HRH3 | |
| SCHEMBL493434 | 0.87 | MEN1 (0.61) | MEN1KMT2ASIGMAR1KDM4ESLC18A3 | |
| SCHEMBL7841889 | 0.86 | SIGMAR1 (0.65) | SIGMAR1HRH3GAA | |
| SCHEMBL1160471 | 0.86 | S1PR5 (0.64) | S1PR5MEN1KMT2AHRH3 | |
| SCHEMBL15532870 | 0.85 | S1PR5 (0.69) | S1PR5SIGMAR1KDM4E | |
| Hydrochloric Acid SCHEMBL1414107 | 0.85 | SIGMAR1 (0.63) | SIGMAR1HRH3GAA | |
| SCHEMBL27475845 | 0.84 | LTA4H (0.66) | S1PR5HRH3 | |
| SCHEMBL6988354 | 0.83 | KDM4E (0.74) | MEN1KMT2AHRH3GAAKDM4E | |
| SCHEMBL27549340 | 0.83 | KDM4E (0.76) | S1PR5MEN1KMT2AKDM4E | |
| SCHEMBL13236630 | 0.83 | S1PR5 (0.66) | S1PR5HRH3GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108129438-A | A kind of compound of the chroman of benzene containing 2- parent nucleus and preparation method thereof | 中国海洋大学 | 2018-06-08 | — | — | CN | disclosed |
| EP-0874809-B1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-27 | — | — | EP | disclosed |
| US-6239175-B1 | Carbamoyloxy derivatives of mutiline and their use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-29 | — | — | US | disclosed |
| US-6020368-A | MICROBIOCIDES | HINKS JEREMY DAVID (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0874809-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997025309-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1997-07-17 | — | — | WO | disclosed |