SCHEMBL2747590

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4548729	0.91	KDR (0.64)	KDRRETMAPK14ABL1EPHA2
	SCHEMBL2749251	0.89	KDR (0.70)	KDRRAF1BRAFFGFR1CSF1R
	SCHEMBL4548728	0.88	KDR (0.70)	KDRRETMAPK14ABL1EPHA2
	SCHEMBL2747600	0.87	KDR (1.00)	KDRAURKALCKAURKBRAF1
	SCHEMBL16620832	0.86	RAF1 (0.74)	KDRRETMAPK14ABL1EPHA2
	SCHEMBL4548761	0.85	KDR (0.66)	KDRRAF1BRAFDDR2
	SCHEMBL2747890	0.85	BRAF (0.59)	KDRRETMAPK14ABL1EPHA2
	SCHEMBL4548756	0.84	KDR (0.64)	KDRRETMAPK14ABL1EPHA2
	SCHEMBL2748022	0.84	KDR (0.64)	KDRRAF1BRAFFGFR1MEN1
	SCHEMBL19888727	0.83	RAF1 (0.75)	KDRRETMAPK14ABL1EPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.