Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.60 |
| ▸ | HTR1A | P08908 | 6/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.57 |
| ▸ | HTR3B | O95264 | 4/20 | 0.57 |
| ▸ | HTR3A | P46098 | 4/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.57 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.57 |
| ▸ | HTR2C | P28335 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27483822 | 0.98 | HTR7 (0.58) | HTR7HTR1AADRB1HTR3EHTR3B | |
| Piperazine SCHEMBL28850703 | 0.98 | HTR7 (0.58) | HTR7HTR1AADRB1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL27355289 | 0.98 | HTR7 (0.58) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL28323356 | 0.91 | HTR7 (0.50) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL27662780 | 0.87 | AGXT (0.56) | SIGMAR1DRD2DRD3ALDH1A1MAPT | |
| SCHEMBL109316 | 0.84 | AGXT (0.67) | ALDH1A1MAPTAGXT | |
| SCHEMBL27581488 | 0.83 | ADRB1 (0.48) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL301359 | 0.83 | ADRB1 (0.62) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL3204004 | 0.83 | HTR7 (0.60) | HTR7HTR1AADRB1HTR3EHTR3B | |
| SCHEMBL7415117 | 0.83 | HTR7 (0.62) | HTR7HTR1AADRB1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452130-A | A kind of Obovatol Mannich base analog derivative and the preparation method and application thereof | UNIV SHANXI AGRICULTURAL | 2019-11-15 | — | — | CN | claimed |
| CN-110437191-A | 13- amino Xanthatin analog derivative and its preparation method and application | UNIV SHANXI AGRICULTURAL | 2019-11-12 | — | — | CN | claimed |
| CN-110337293-A | Therapeutic compound | 新泽西鲁特格斯州立大学 | 2019-10-15 | — | — | CN | claimed |
| CN-106699690-A | Pleuromulin derivative with acyl piperazine side chain and preparing method and application of pleuromulin derivative | 华南农业大学 | 2017-05-24 | — | — | CN | claimed |
| CN-104507950-B | Thienopyrimidines | 拜耳医药股份有限公司 | 2017-03-22 | — | — | CN | claimed |
| CN-102797043-B | Medicinal molecular fragment library and construction process thereof | Tianli (Tianjin) Technology Co., Ltd. (CN) | 2015-11-25 | — | — | CN | claimed |
| CN-102797043-A | Medicinal molecular fragment library and construction method thereof | CBB NETWORK CO LTD | 2012-11-28 | — | — | CN | claimed |
| CN-106420754-B | The purposes of benzo five-membered Azacyclyl bridged piperazine derivatives | 沈阳海王生物技术有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-110354267-A | Method and composition for low blood pressure recovery | 法尔麦兹公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-110337293-A | Therapeutic compound | 新泽西鲁特格斯州立大学 | 2019-10-15 | — | — | CN | disclosed |
| CN-107573302-B | Aryl piperazines compound and its preparation method and application | 袁牧 | 2019-09-20 | — | — | CN | disclosed |
| CN-106699690-B | A kind of pleuromutilin derivative and its preparation method and application with acyl piperazine base side chain | 华南农业大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-104926801-B | Substituted azetidine analog derivative, the pharmaceutical composition containing it and its application in antitumor | 浙江大学 | 2019-06-04 | — | — | CN | disclosed |
| CN-1145609-C | Piperazine compounds and medical use thereof | ������ҩ��ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| CN-1306526-A | Novel heterocyclically substituted amides with cysteine protease-inhibiting effect | BASF AG (DE) | 2001-08-01 | — | — | CN | disclosed |
| CN-1281438-A | Piperazine compounds and their use as pharmaceuticals | EFUKU CO LTD (JP) | 2001-01-24 | — | — | CN | disclosed |
| CN-1271363-A | 3' -N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity | ABBOTT LAB (US) | 2000-10-25 | — | — | CN | disclosed |
| CN-1261347-A | Remedies/preventives for frequent urination/urinary incontinence and tropone derivatives | NIPPON KAYAKU KK (JP) | 2000-07-26 | — | — | CN | disclosed |
| CN-1237183-A | 6-0-substituted ketolides with antibacterial activity | ABBOTT CO (US) | 1999-12-01 | — | — | CN | disclosed |
| CN-1224427-A | 6-O-substituted erythromycin compounds and preparation method thereof | ABBOTT LAB (US) | 1999-07-28 | — | — | CN | disclosed |