Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | MAX | P61244 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811054 | 0.75 | GRM2 (0.44) | POLBMAPT | |
| SCHEMBL14722693 | 0.71 | CTSV (0.45) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL11422374 | 0.70 | CYP19A1 (0.50) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL10409122 | 0.70 | NPC1 (0.55) | CYP19A1POLBMAPTMYCMAX | |
| SCHEMBL30184780 | 0.69 | CTSV (0.51) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL1040246 | 0.69 | CTSV (0.51) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL7907625 | 0.69 | MEN1 (0.54) | CYP11B1CYP11B2POLBMAPTMYC | |
| SCHEMBL3926941 | 0.68 | KMT2A (0.53) | POLBMAPTMYCMAXABCB1 | |
| SCHEMBL30189830 | 0.68 | KMT2A (0.53) | POLBMAPTMYCMAXABCB1 | |
| SCHEMBL7116860 | 0.68 | POLB (0.56) | CYP11B1CYP11B2CYP19A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1160051-A | New substituted oxazolidinones | BAYER AG (DE) | 1997-09-24 | — | — | CN | disclosed |