SCHEMBL7811054

SCHEMBL7811054

NC[C@H]1CN(c2ccc([N+](=O)[O-])c(OCc3ccccc3)c2)C(=O)O1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 8/20 0.44
F10 P00742 1/20 0.41
MAPT P10636 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8991341 0.92 POLB (0.47) GRM2F10POLB
SCHEMBL7829917 0.82 MAOA (0.47) GRM2POLB
SCHEMBL2837784 0.82 GRM2 (0.47) GRM2F10
SCHEMBL8991499 0.78 POLB (0.47) GRM2POLB
SCHEMBL8991536 0.78 MAOA (0.49) F10POLB
SCHEMBL27477172 0.75 CYP11B1 (0.41) MAPTPOLB
SCHEMBL8991532 0.73 ABCB1 (0.44) MAPTPOLB
SCHEMBL3205152 0.73 GRM2 (0.48) GRM2F10
SCHEMBL9611100 0.73 GRM2 (0.49) GRM2
SCHEMBL14168113 0.72 F10 (0.57) GRM2F10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789025-B1 Substituted oxazolidinone and their use as antibacterial medicine BAYER AG (DE) 2001-04-04 EP disclosed
US-5792765-A ANTIBACTERIAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 1998-08-11 US disclosed
CN-1160051-A New substituted oxazolidinones BAYER AG (DE) 1997-09-24 CN disclosed
EP-0789025-A1 Substituted oxazolidinone and their use as antibacterial medicine BAYER AG (DE) 1997-08-13 EP disclosed