Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27501691 | 0.87 | KDM4E (0.52) | HDAC1HDAC6HDAC8KDM4ENPC1 | |
| SCHEMBL3424662 | 0.78 | KDM4E (0.68) | KDM4ENPC1HSD17B10MAPK1MEN1 | |
| SCHEMBL27463009 | 0.76 | HDAC6 (0.50) | HDAC1HDAC6HDAC8LMNA | |
| SCHEMBL3059145 | 0.72 | NPC1 (0.56) | KDM4ENPC1HSD17B10MAPK1MEN1 | |
| SCHEMBL9911643 | 0.71 | RAB9A (0.70) | KDM4ENPC1HSD17B10MEN1KMT2A | |
| SCHEMBL3420990 | 0.68 | KDM4E (0.53) | HDAC1KDM4ENPC1HSD17B10MAPK1 | |
| SCHEMBL2972148 | 0.68 | KDM4E (0.63) | KDM4ENPC1HSD17B10MAPK1MEN1 | |
| SCHEMBL27463889 | 0.67 | KDM4E (0.47) | KDM4ENPC1HSD17B10MAPK1MEN1 | |
| SCHEMBL9081166 | 0.67 | KDM4E (0.61) | KDM4ENPC1HSD17B10MAPK1MEN1 | |
| SCHEMBL2932828 | 0.67 | KDM4E (0.61) | KDM4ENPC1HSD17B10MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1159188-A | Herbicidal pyrazine derivatives | BASF AG (DE) | 1997-09-10 | — | — | CN | disclosed |