Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26332190 | 0.91 | MEN1 (0.58) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL23182183 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL4512048 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL13713184 | 0.85 | KDM4E (0.62) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL4509936 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL4509940 | 0.83 | KDM4E (0.60) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL3844177 | 0.82 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL18125935 | 0.82 | ALDH1A1 (0.71) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL14468540 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 | |
| SCHEMBL14160581 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDCYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |