Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20280108 | 0.87 | TLR7 (0.48) | ACSS2KDM4EALDH1A1HTTDRD2 | |
| SCHEMBL29559474 | 0.87 | TLR7 (0.48) | ACSS2KDM4EALDH1A1HTTDRD2 | |
| Hydrochloric Acid SCHEMBL20266404 | 0.86 | TLR7 (0.47) | ACSS2KDM4EALDH1A1HTTDRD2 | |
| SCHEMBL27478604 | 0.84 | MC4R (0.45) | ACSS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL25767043 | 0.83 | ACSS2 (0.46) | ACSS2KDM4EALDH1A1DRD2TBXA2R | |
| SCHEMBL24265281 | 0.80 | ACSS2 (0.49) | ACSS2KDM4EALDH1A1HTTDRD2 | |
| SCHEMBL20266433 | 0.78 | ACSS2 (0.46) | ACSS2KDM4ELMNAHTTDRD2 | |
| SCHEMBL30676114 | 0.78 | ACSS2 (0.46) | ACSS2KDM4ELMNAHTTDRD2 | |
| SCHEMBL31143264 | 0.78 | TP53 (0.50) | ACSS2KDM4EALDH1A1HTTDRD2 | |
| SCHEMBL27478697 | 0.77 | ACSS2 (0.43) | ACSS2KDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562006-A1 | N-HETEROCYLIC GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | Carmot Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026338-A1 | N-HETEROCYLIC GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026338-A1 | N-HETEROCYLIC GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |