Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27478558 | 0.91 | GLP1R (0.48) | HDAC6GLP1R | |
| SCHEMBL27478591 | 0.84 | ACSS2 (0.45) | SMN1; SMN2ALDH1A1ACSS2 | |
| SCHEMBL22009843 | 0.79 | GLP1R (0.51) | GLP1ROPRK1ALDH1A1ACSS2GAA | |
| SCHEMBL30676073 | 0.79 | GLP1R (0.51) | GLP1ROPRK1ALDH1A1ACSS2GAA | |
| SCHEMBL27478667 | 0.79 | GLP1R (0.48) | MC4RHDAC6GLP1ROPRK1MLLT1 | |
| SCHEMBL27477879 | 0.77 | GLP1R (0.50) | GLP1R | |
| SCHEMBL27479426 | 0.77 | GLP1R (0.37) | GLP1RSMN1; SMN2CYP2D6 | |
| SCHEMBL22009801 | 0.76 | GLP1R (0.48) | GLP1RACSS2 | |
| SCHEMBL24791812 | 0.76 | GLP1R (0.51) | GLP1R | |
| SCHEMBL27479069 | 0.76 | MC4R (0.43) | MC4RHDAC6GLP1ROPRK1MLLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026338-A1 | N-HETEROCYLIC GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |