Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27478697 | 1.00 | ACSS2 (0.43) | ACSS2KDM4ETP53MAPTTHRB | |
| SCHEMBL26237230 | 0.89 | ACSS2 (0.46) | ACSS2KDM4ETP53MAPTTHRB | |
| SCHEMBL31202954 | 0.89 | ACSS2 (0.46) | ACSS2KDM4ETP53MAPTTHRB | |
| SCHEMBL30474209 | 0.86 | TLR7 (0.48) | ACSS2KDM4ETP53MAPTTHRB | |
| SCHEMBL31143264 | 0.84 | TP53 (0.50) | ACSS2KDM4ETP53MAPTTHRB | |
| SCHEMBL27478703 | 0.80 | GLP1R (0.38) | ACSS2MAPTALDH1A1HPGD | |
| SCHEMBL24265281 | 0.80 | ACSS2 (0.49) | ACSS2KDM4EDRD2TBXA2RALOX15 | |
| SCHEMBL25373333 | 0.79 | ACSS2 (0.42) | ACSS2LMNA | |
| SCHEMBL25373335 | 0.79 | ACSS2 (0.42) | ACSS2LMNA | |
| SCHEMBL26541102 | 0.79 | LMNA (0.38) | ACSS2ALDH1A1LMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026338-A1 | N-HETEROCYLIC GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |