Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104892 | 0.85 | IRAK4 (0.70) | IRAK4HSD17B10KDM4EHPGDCYP2C9 | |
| Benzene SCHEMBL27809575 | 0.84 | IRAK4 (0.68) | IRAK4HSD17B10KDM4EHPGDCYP2C9 | |
| Bicarbonate SCHEMBL21811920 | 0.84 | IRAK4 (0.68) | IRAK4HSD17B10KDM4EHPGDCYP2C9 | |
| SCHEMBL10763308 | 0.84 | IRAK4 (0.68) | IRAK4HSD17B10KDM4EHPGDCYP2C9 | |
| Bicarbonate SCHEMBL236925 | 0.84 | IRAK4 (0.68) | IRAK4HSD17B10KDM4EHPGDCYP2C9 | |
| Bicarbonate SCHEMBL29943521 | 0.84 | IRAK4 (0.68) | IRAK4HSD17B10KDM4EHPGDCYP2C9 | |
| SCHEMBL7792695 | 0.82 | SMN1; SMN2 (0.55) | IRAK4KDM4EHPGDALDH1A1 | |
| SCHEMBL7794937 | 0.82 | FABP3 (0.49) | IRAK4HSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL31634047 | 0.81 | IRAK4 (0.50) | IRAK4HSD17B10CYP2C9ALDH1A1CA1 | |
| SCHEMBL3632568 | 0.81 | IRAK4 (0.50) | IRAK4HSD17B10CYP2C9ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1160309-C | Alkyloxyamino substituted fluorenones and their use as protein kinase cinhibitors | �ճ�˹�������³˹��˾ | 2004-08-04 | — | — | CN | disclosed |
| CN-1220660-A | Alkyloxyamino substituted fluorenones and their use as protein kinase cinhibitors | HOECHST MARION ROUSSEL INC (US) | 1999-06-23 | — | — | CN | disclosed |