Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.33 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10204881 | 0.79 | TAAR1 (0.39) | TAAR1SLC6A4HTR2CHTR2AIDO1 | |
| SCHEMBL14949126 | 0.77 | IDO1 (0.40) | TAAR1SLC6A4HTR2CHTR2AIDO1 | |
| SCHEMBL27514918 | 0.75 | IDO1 (0.55) | TAAR1IDO1LMNAMAPTHTT | |
| SCHEMBL10204883 | 0.75 | TAAR1 (0.39) | TAAR1SLC6A4MAPK1MAP2K4MAPKAPK2 | |
| SCHEMBL18213815 | 0.74 | IDO1 (0.38) | TAAR1SLC6A4HTR2CHTR2AIDO1 | |
| SCHEMBL13229385 | 0.74 | ALDH1A1 (0.47) | LMNAHTTTDP1 | |
| SCHEMBL13034141 | 0.71 | ALDH1A1 (0.51) | LMNA | |
| SCHEMBL8239069 | 0.71 | TAAR1 (0.43) | TAAR1MAPK1MAP2K4MAPKAPK2MAPKAPK3 | |
| SCHEMBL10290674 | 0.71 | TAAR1 (0.43) | TAAR1MAPK1MAP2K4MAPKAPK2MAPKAPK3 | |
| SCHEMBL268243 | 0.70 | MAPK1 (0.54) | TAAR1MAPK1MAP2K4MAPKAPK2MAPKAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190437-C | pteridine compound for treating psoriasis | ASTRAZENECA AB (SE) | 2005-02-23 | — | — | CN | disclosed |
| CN-1404482-A | Pteridine compounds for the treatment of psoriasis | ASTRAZENECA AB (SE) | 2003-03-19 | — | — | CN | disclosed |