Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877726 | 0.79 | MAPT (0.45) | L3MBTL1MAPTLMNATP53KDM4E | |
| SCHEMBL7880056 | 0.77 | L3MBTL1 (0.50) | L3MBTL1MAPTLMNATP53KDM4E | |
| SCHEMBL7879482 | 0.77 | L3MBTL1 (0.50) | L3MBTL1MAPTLMNATP53KDM4E | |
| SCHEMBL7881808 | 0.76 | L3MBTL1 (0.49) | L3MBTL1MAPTLMNATP53KDM4E | |
| SCHEMBL7884307 | 0.74 | DRD2 (0.45) | BRD4 | |
| SCHEMBL19013553 | 0.73 | NR1H2 (0.40) | L3MBTL1CYP1A2CYP2C19NR1H2 | |
| SCHEMBL29631893 | 0.73 | NR1H2 (0.40) | L3MBTL1CYP1A2CYP2C19NR1H2 | |
| SCHEMBL29631908 | 0.72 | NR1H2 (0.39) | L3MBTL1MAPTLMNANR1H2ALDH1A1 | |
| SCHEMBL19013604 | 0.72 | NR1H2 (0.39) | MAPTCYP1A2PKMCYP2C19MAPK14 | |
| SCHEMBL19013556 | 0.72 | NR1H2 (0.39) | L3MBTL1MAPTLMNANR1H2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1106800-A | Indoloylguanidine derivatives | SUMITOMO PHARMA (JP) | 1995-08-16 | — | — | CN | disclosed |