SCHEMBL2748040

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4548904	0.89	KDR (0.75)	KDRRETRAF1BRAFFLT1
	SCHEMBL2747491	0.87	KDR (0.78)	KDRRETRAF1BRAFFLT1
	SCHEMBL4548992	0.87	KDR (0.72)	KDRRETRAF1BRAFFLT1
	SCHEMBL2746145	0.86	KDR (0.80)	KDRRETRAF1BRAFFLT1
	SCHEMBL2437469	0.86	KDR (0.71)	KDRRETRAF1BRAFFLT1
	SCHEMBL2747600	0.86	KDR (1.00)	KDRRAF1BRAFFLT1FLT4
	SCHEMBL2747900	0.85	KDR (0.78)	KDRRETRAF1BRAFFLT1
	SCHEMBL2747739	0.85	KDR (0.84)	KDRRETBRAFFLT1FLT4
	SCHEMBL2748188	0.85	KDR (0.81)	KDRBRAFFLT1FLT4FGFR1
	SCHEMBL2747529	0.84	KDR (0.80)	KDRRETBRAFFLT1FLT4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.