SCHEMBL27480613

SCHEMBL27480613

COC(C)C(c1ccc(C#N)cc1)C(C)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HTT P42858 1/20 0.41
CYP19A1 P11511 7/20 0.39
HRH3 Q9Y5N1 3/20 0.38
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CA12 O43570 1/20 0.37
CA2 P00918 1/20 0.37
CA3 P07451 1/20 0.37
CA6 P23280 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
GRIA1 P42261 1/20 0.36
GRIA2 P42262 1/20 0.36
GRIA3 P42263 1/20 0.36
GRIA4 P48058 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27478093 0.84 HTT (0.35) CYP2A6ALDH1A1HTTCYP19A1KDM4E
SCHEMBL30187789 0.79 CYP19A1 (0.46) CYP2A6ALDH1A1HTTCYP19A1HRH3
SCHEMBL7385564 0.77 CYP2A6 (0.46) CYP2A6ALDH1A1HTTCYP19A1KDM4E
SCHEMBL2266164 0.77 CYP2A6 (0.46) CYP2A6ALDH1A1HTTCYP19A1KDM4E
SCHEMBL25920912 0.75 CYP2A6 (0.44) CYP2A6ALDH1A1CYP19A1KDM4EGAA
SCHEMBL11032485 0.74 KIF11 (0.46) CYP2A6ALDH1A1CYP19A1CA12CA2
SCHEMBL6205272 0.73 CYP2A6 (0.43) CYP2A6ALDH1A1HTTCYP19A1KDM4E
SCHEMBL6205271 0.73 CYP2A6 (0.43) CYP2A6ALDH1A1HTTCYP19A1KDM4E
SCHEMBL6077332 0.73 CYP2A6 (0.43) CYP2A6ALDH1A1HTTCYP19A1CA12
SCHEMBL7799578 0.73 CYP2A6 (0.52) CYP2A6ALDH1A1CYP19A1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024126619-A1 ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A COMPOUND OF FORMULA (II), AND DISPLAY DEVICE COMPRISING THE ORGANIC ELECTROLUMINESCENT DEVICE NOVALED GMBH (DE) 2024-06-20 WO disclosed