Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757015 | 0.86 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAOAKDM1APPARG | |
| SCHEMBL30702419 | 0.79 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2MAOAKDM1APPARG | |
| SCHEMBL1046284 | 0.79 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2MAOAKDM1APPARG | |
| SCHEMBL27757096 | 0.79 | GSK3B (0.48) | ALDH1A1SMN1; SMN2KDM1APPARGGSK3B | |
| Iodide SCHEMBL8924984 | 0.78 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2MAOAKDM1APPARG | |
| SCHEMBL31571120 | 0.78 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MAOAKDM1APPARG | |
| SCHEMBL1573679 | 0.78 | PPARG (0.37) | ALDH1A1SMN1; SMN2MAOAKDM1APPARG | |
| SCHEMBL29973993 | 0.78 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MAOAKDM1APPARG | |
| SCHEMBL9305366 | 0.78 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MAOAKDM1APPARG | |
| SCHEMBL1412788 | 0.78 | PPARG (0.37) | ALDH1A1SMN1; SMN2MAOAKDM1APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478366-A | A kind of preparation method of 1,2- pentanediol | 衡阳春天医药化工设备有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-120025293-A | Difunctional aza-carbene catalyst and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2025-05-23 | — | — | CN | disclosed |
| CN-112442038-B | Industrial preparation method of pemetrexed disodium | 德州德药制药有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-112174970-B | Method for preparing pemetrexed disodium with high yield | 德州德药制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-109704921-B | Economic and green preparation method of vicinal dihydric alcohol | 淄博诺奥化工有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-112442038-A | Industrial preparation method of pemetrexed disodium | 德州德药制药有限公司 | 2021-03-05 | — | — | CN | disclosed |
| CN-112174970-A | Method for preparing pemetrexed disodium in high yield | 德州德药制药有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-109704921-A | The economical and eco-friendly preparation method of adjacent dihydric alcohol | 淄博诺奥化工股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-106478366-A | A kind of preparation method of 1,2- pentanediol | 衡阳春天医药化工设备有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106478366-A | A kind of preparation method of 1,2- pentanediol | 衡阳春天医药化工设备有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-101489998-B | Process for producing 2-hydroxy-4- (methylthio) butanoic acid or butyrate compound and intermediate thereof | SUMITOMO CO LTD | 2013-01-02 | — | — | CN | disclosed |
| US-8178325-B2 | Process for producing sulfur-containing hydroxycarboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-15 | — | — | US | disclosed |
| CN-101517087-B | Process for the preparation of 2-hydr0xy-4- (alkylthio or arylthio) butanoic acid by microbial conversion of 2-0x0-4- (alkylthio or arylthio) 1-butanol employing bacteria of the genus pseud0m0nas, rh0 | SUMITOMO CHEMICAL CO | 2011-11-23 | — | — | CN | disclosed |
| EP-2066798-B1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY CARBOXYLIC ACIDS EMPLOYING BACTERIA OF THE GENUS PSEUDOMONAS, RHODOCOCCUS OR BACILLUS | SUMITOMO CHEMICAL CO (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-20090275094-A1 | PROCESS FOR PRODUCING SULFUR-CONTAINING HYDROXYCARBOXYLIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-11-05 | — | — | US | disclosed |
| CN-101517087-A | Process for the preparation of 2-hydr0xy-4- (alkylthio or arylthio) butanoic acid by microbial conversion of 2-0x0-4- (alkylthio or arylthio) 1-butanol employing bacteria of the genus pseud0m0nas, rh0 | SUMITOMO CHEMICAL CO (JP) | 2009-08-26 | — | — | CN | disclosed |
| CN-101489998-A | Process for producing 2-hydroxy-4- (methylthio) butanoic acid or butyrate compound and intermediate thereof | SUMITOMO CHEMICAL CO (JP) | 2009-07-22 | — | — | CN | disclosed |
| EP-2066798-A1 | PROCESS FOR THE PREPARATION OF 2-HYDR0XY-4- (ALKYLTHIO OR ARYLTHIO) BUTANOIC ACID BY MICROBIAL CONVERSION OF 2-0X0-4- (ALKYLTHIO OR ARYLTHIO) 1-BUTANOL EMPLOYING BACTERIA OF THE GENUS PSEUD0M0NAS, RH0D0C0CCUS, OR BACILLUS | Sumitomo Chemical Company, Limited (JP) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008104875-A1 | OXAZOLIDINONES AS CHOLESTEROL ABSORPTION INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-09-04 | — | — | WO | disclosed |
| WO-2008038810-A1 | PROCESS FOR THE PREPARATION OF 2-HYDR0XY-4- (ALKYLTHIO OR ARYLTHIO) BUTANOIC ACID BY MICROBIAL CONVERSION OF 2-0X0-4- (ALKYLTHIO OR ARYLTHIO) 1-BUTANOL EMPLOYING BACTERIA OF THE GENUS PSEUD0M0NAS, RH0D0C0CCUS, OR BACILLUS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-04-03 | — | — | WO | disclosed |