SCHEMBL1046284

SCHEMBL1046284

CCN1c2ccccc2SC1C

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ MAOA P21397 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ KDM1A O60341 2/20 0.36
▸ PPARG P37231 1/20 0.35
▸ GSK3B P49841 2/20 0.35
▸ BCHE P06276 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30702419 1.00 SMN1; SMN2 (0.38) SMN1; SMN2ALDH1A1MAOAMEN1POLB
Iodide SCHEMBL8924984 0.98 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1MAOAMEN1POLB
SCHEMBL16709169 0.86 MAOA (0.38) SMN1; SMN2MAOAMEN1POLBKMT2A
SCHEMBL16709179 0.86 MAOA (0.42) SMN1; SMN2ALDH1A1MAOAMEN1POLB
SCHEMBL1049071 0.85 POLB (0.40) SMN1; SMN2ALDH1A1MAOAMEN1POLB
Quinoline SCHEMBL28758483 0.83 ALDH1A1 (0.45) SMN1; SMN2ALDH1A1MEN1POLBKMT2A
SCHEMBL6313787 0.82 KDM1A (0.43) SMN1; SMN2ALDH1A1MAOAPOLBKDM1A
SCHEMBL21803246 0.81 KDM1A (0.39) ALDH1A1KDM1AGSK3BBCHE
SCHEMBL8861416 0.81 LMNA (0.37) SMN1; SMN2ALDH1A1MEN1POLBKMT2A
SCHEMBL7534194 0.80 MAOA (0.37) SMN1; SMN2ALDH1A1MAOAMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263928-A Fluorescent probe and preparation method thereof 南通大学 2023-12-22 — — CN claimed
EP-1655132-B2 Positive photosensitive lithographic printing plate AGFA GRAPHICS NV (BE) 2017-08-23 — — EP claimed
CN-106916140-A Carbazole nitrogen containing derivative and its production and use 山西大学 2017-07-04 — — CN claimed
CN-105566247-A Benzothiazole croconium colorimetric probe, preparation method and application UNIV CHANGZHOU 2016-05-11 — — CN claimed
CN-103251513-A Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition OREAL 2013-08-21 — — CN claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 — — EP claimed
EP-1655132-B1 Positive photosensitive lithographic printing plate AGFA GRAPHICS NV (BE) 2011-10-12 — — EP claimed
US-8034125-B2 Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition L'OREAL S.A. (FR) 2011-10-11 — — US claimed
EP-2205681-B1 DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION OREAL (FR) 2011-08-31 — — EP claimed
US-20110016642-A1 DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION L'OREAL S.A. (FR) 2011-01-27 — — US claimed
US-20050048000-A1 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2005-03-03 — — US claimed
EP-1194118-B1 AGENT FOR COLORING FIBERS WELLA AG (DE) 2004-09-15 — — EP claimed
US-6790239-B1 COMBINATION OF AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-09-14 — — US claimed
US-6770102-B1 AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS; DOES NOT REQUIRE OXIDIZING AGENT; BRILLIANCE; COLOR DEPTH; WIDE VARIETY OF SHADES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-08-03 — — US claimed
EP-1303311-A2 AMYLOID TARGETING IMAGING AGENTS AND USES THEREOF Neurochem, Inc. (CA) 2003-04-23 — — EP claimed
US-20020115717-A1 Amyloid targeting imaging agents and uses thereof NEUROCHEM (INTERNATIONAL) LIMITED (GI) 2002-08-22 — — US claimed
WO-2002007781-A2 AMYLOID TARGETING IMAGING AGENTS AND USES THEREOF NEUROCHEM INC. (CA) 2002-01-31 — — WO claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 — — EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 — — EP claimed
EP-0615854-B1 Recording sheets containing cationic sulphur compounds XEROX CORP (US) 1997-06-04 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110016642-A1 DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION KRT18, SQOR, TST SMN1; SMN2 4562/4885ALDH1A1 743/4885MAOA 1255/4885
US-20050048000-A1 Amyloid targeting imaging agents and uses thereof APP, APBA1, BACE1 SMN1; SMN2 1267/4885ALDH1A1 3305/4885MAOA 886/4885
US-20020115717-A1 Amyloid targeting imaging agents and uses thereof APP, APBA1, BACE1 SMN1; SMN2 1267/4885ALDH1A1 3305/4885MAOA 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback