Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 4/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 12/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501877 | 0.78 | KIF11 (0.50) | HTTALDH1A1HSD17B10KIF11JAK2 | |
| SCHEMBL8757524 | 0.78 | PARP14 (0.55) | HTTALDH1A1HSD17B10KIF11JAK2 | |
| SCHEMBL9157046 | 0.77 | KMT2A (0.45) | HTTKDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL11449722 | 0.75 | EGFR (0.54) | HTTKDM4EHSD17B10KIF11JAK2 | |
| SCHEMBL9490444 | 0.75 | KIF11 (0.59) | HTTKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL4784858 | 0.74 | ALDH1A1 (0.44) | HTTKDM4EALDH1A1LMNATP53 | |
| SCHEMBL31497264 | 0.74 | KMT2A (0.59) | KDM4EALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL896623 | 0.74 | KMT2A (0.59) | KDM4EALDH1A1MAPK1HSD17B10TP53 | |
| SCHEMBL29376743 | 0.73 | KIF11 (0.49) | HTTKDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL241852 | 0.73 | KIF11 (0.49) | HTTKDM4EALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531641-A | Oxazoline ring-containing compound, material for electron transport/injection layer containing the same, and organic electroluminescent element using the same | 捷恩智株式会社 | 2018-01-02 | — | — | CN | disclosed |
| CN-1169789-C | Aminoalkoxy carbazoles for the treatment of CNS diseases | 法玛西雅厄普约翰美国公司 | 2004-10-06 | — | — | CN | disclosed |
| CN-1372547-A | Aminoalkoxy carbazoles for the treatment of CNS diseases | UPJOHN CO (US) | 2002-10-02 | — | — | CN | disclosed |