SCHEMBL274817

SCHEMBL274817

CCCCCC[Si](C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
THRB P10828 1/20 0.53
DNM1 Q05193 7/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC22A1 O15245 1/20 0.40
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13656438 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL18079767 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28647432 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL270268 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5664939 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL25241608 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL3971101 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL3915336 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6565540 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL27938627 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
CN-114341072-B Textured glass articles and methods of making the same 康宁股份有限公司 2023-11-14 CN claimed
WO-2022221354-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-10-20 WO claimed
CN-115057994-A Olefin metathesis polymerization method based on diazo monomer and polymer thereof 安徽大学 2022-09-16 CN claimed
CN-108671776-A A kind of solvent resistant water-in-oil emulsion seperation film and preparation method thereof 四川大学 2018-10-19 CN claimed
US-12628601-B2 Filter structure and substrate treating system including filter structure SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-05-12 US disclosed
CN-118459484-A N-type organic molecules with near infrared response and application thereof 广州光达创新科技有限公司 2024-08-09 CN disclosed
WO-2024160042-A1 ORGANIC PHOTOSENSITIVE MOLECULE HAVING SPECTRAL RESPONSE REACHING INFRARED REGION, AND USE THEREOF 广州光达创新科技有限公司 2024-08-08 WO disclosed
CN-115057994-B Olefin metathesis polymerization method based on diazonium monomer and polymer thereof 安徽大学 2024-07-30 CN disclosed
CN-118325095-A Modified silicone oil and preparation method and application thereof 山东诺唯亚新材料有限公司 2024-07-12 CN disclosed
CN-118290445-A Preparation method and application of deuterated quinoid end-capped N-type organic molecules with short-wave infrared response and deuterated quinoid end groups 广州光达创新科技有限公司 2024-07-05 CN disclosed
CN-113814888-B Polishing sheet, method for manufacturing the same, and method for manufacturing semiconductor device using the same SK恩普士有限公司 2024-06-18 CN disclosed
US-4794145-A REACTING WITH ALKYL SUBSTITUTED STYRENE, THEN MONOMER THE DOW CHEMICAL COMPANY (US) 1988-12-27 US disclosed
US-4786689-A Process for metallating nonconjugated diene-containing ethylene polymers and graft polymers prepared therefrom THE DOW CHEMICAL COMPANY (US) 1988-11-22 US disclosed
US-4761456-A ALKYLLITHIUM, POTASSIUM ALKOXIDE, TERTIARY DIAMINE THE DOW CHEMICAL COMPANY (US) 1988-08-02 US disclosed
US-4636229-A FUMARIC DIESTER POLYMER NIPPON OIL COMPANY, LIMITED (JP) 1987-01-13 US disclosed
EP-0022979-B1 THERMOPLASTIC RESIN COMPOSITION HAVING GOOD HEAT CYCLE PROPERTY Sumitomo Naugatuck Co., Ltd. (JP) 1984-02-08 EP disclosed
US-4305856-A POLYCARBONATE, ABS RESIN, ORGANOSILICON COMPOUND SUMITOMO NAUGATUCK CO., LTD. (JP) 1981-12-15 US disclosed
US-4228051-A Thermoplastic resin composition having good heat cycle property SUMITOMO NAUGATUCK CO., LTD. (JP) 1980-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12628601-B2 Filter structure and substrate treating system including filter structure TMEM63A, SNX2, SNX9 TSHR 3057/4885THRB 4830/4885DNM1 3507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.