SCHEMBL270268

SCHEMBL270268

CCCCCCCC[Si](C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
THRB P10828 1/20 0.53
DNM1 Q05193 7/20 0.40
ALDH1A1 P00352 3/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC22A1 O15245 1/20 0.40
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13656438 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL274817 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL18079767 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28647432 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5664939 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL25241608 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL3971101 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL3915336 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6565540 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL27938627 1.00 TSHR (0.53) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119842155-A High-strength durable pipe filling master batch and production process thereof 湖南登科材料科技有限公司 2025-04-18 CN claimed
CN-119431054-A Preparation method of super-hydrophobic attapulgite-based slow-release urea 石彦龙 2025-02-14 CN claimed
EP-3678761-B1 METHODS FOR PREPARING SUPPORTED ZEOLITE FILMS ZEOMEM SWEDEN AB (SE) 2024-12-18 EP claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
CN-117925091-A Anti-fouling self-cleaning material and preparation method thereof 南京水滴智能环保装备研究院有限公司 2024-04-26 CN claimed
CN-117846214-A Anti-icing and anti-condensation building board and preparation method thereof 上海二十冶建设有限公司 2024-04-09 CN claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
US-11554359-B2 Supported zeolite films and methods for preparing ZEOMEM SWEDEN AB (SE) 2023-01-17 US claimed
CN-111065447-B Supported zeolite membrane and preparation method J·赫德伦 2022-10-21 CN claimed
WO-2022221354-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-10-20 WO claimed
WO-2011028320-A2 DISPERSIONS OF INORGANIC PARTICULATES CONTAINING ALKOXYCRYLENE HALLSTAR INNOVATIONS CORP. (US) 2011-03-10 WO claimed
US-7413730-B2 Cosmetic and dermatological light protection formulations BEIERSDORF AG (DE) 2008-08-19 US claimed
US-7211637-B2 Sterically hindered reagents for use in single component siloxane cure systems THERM-O-DISC, INCORPORATED (US) 2007-05-01 US claimed
US-20060034785-A1 Cosmetic and dermatological light protection formulations BEIERSDORF AG 2006-02-16 US claimed
EP-1602691-A1 Sterically hindered reagents for use in single component siloxane cure systems Therm-o-Disc Incorporated (US) 2005-12-07 EP claimed
EP-0881880-B1 STABLE LIQUID ANTIMICROBIAL SUSPENSIONS OF QUATERNARY 3,5,7-TRIAZA-1-AZONIAADAMANTANE DERIVATIVES DOW CHEMICAL CO (US) 2002-06-05 EP claimed
EP-0966954-B1 Cosmetic sunscreen compositions containing a metal oxide nanopigment and an acrylic terpolymer and use of these compositions for protection keratinic materials against UV-radiation OREAL (FR) 2002-02-20 EP claimed
US-6174517-B1 Compositions containing a dibenzoylmethane derivative and a titanium oxide nanopigment, and uses SOCIETE L'OREAL S.A. (FR) 2001-01-16 US claimed
US-6060041-A Photoprotective cosmetic compositions containing a metal oxide nanopigment and an acrylic terpolymer, and use of these compositions for protecting keratinous material against ultraviolet radiation L'OREAL (FR) 2000-05-09 US claimed
EP-0748624-B1 Composition containing a dibenzoylmethane derivative and a nanopigment of titanium dioxide and uses thereof OREAL (FR) 1998-04-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060034785-A1 Cosmetic and dermatological light protection formulations USP30, CUTA, USP28 TSHR 2481/4885THRB 2338/4885DNM1 4518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.