Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310770 | 0.89 | SMN1; SMN2 (0.57) | SMN1; SMN2POLBLMNAHPGDALDH1A1 | |
| SCHEMBL2180524 | 0.86 | GAA (0.51) | SMN1; SMN2POLBALDH1A1GAACHRM1 | |
| SCHEMBL22440438 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBLMNAHPGDMMP13 | |
| SCHEMBL3708900 | 0.80 | LMNA (0.54) | SMN1; SMN2POLBLMNAHPGDALDH1A1 | |
| SCHEMBL3652385 | 0.80 | LMNA (0.54) | SMN1; SMN2POLBLMNAHPGDALDH1A1 | |
| SCHEMBL3652388 | 0.80 | LMNA (0.54) | SMN1; SMN2POLBLMNAHPGDALDH1A1 | |
| SCHEMBL2778566 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2POLBLMNAHPGDMMP13 | |
| SCHEMBL12468318 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBLMNAHPGDMMP13 | |
| SCHEMBL12468883 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBLMNAHPGDMMP13 | |
| SCHEMBL12468881 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBLMNAHPGDMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1171870-C | Cysteine protease inhibitors | ʷ��˿�������ȳ�ķ����˾ | 2004-10-20 | — | — | CN | disclosed |
| CN-1232399-A | Cysteine protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 1999-10-20 | — | — | CN | disclosed |