Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245943 | 0.82 | SMN1; SMN2 (0.37) | NPC1RAB9ASMN1; SMN2TRPM8PARP15 | |
| SCHEMBL27487201 | 0.81 | HTT (0.33) | — | |
| SCHEMBL27660661 | 0.76 | ALOX15 (0.39) | NPC1RAB9ASMN1; SMN2TRPM8PARP15 | |
| SCHEMBL6642025 | 0.76 | — | — | |
| SCHEMBL185066 | 0.74 | — | — | |
| SCHEMBL28661586 | 0.73 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL5229371 | 0.72 | — | — | |
| SCHEMBL4233726 | 0.68 | THRB (0.34) | RAB9A | |
| SCHEMBL25840171 | 0.68 | PARP15 (0.36) | NPC1RAB9ASMN1; SMN2TRPM8PARP15 | |
| SCHEMBL27984234 | 0.68 | PARP15 (0.42) | TRPM8PARP15PARP10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1188471-A | 1,4-disubstituted piepridine derivatives | BANYU PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |