Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25434590 | 0.82 | CHRM2 (0.41) | CHRM2CHRM1KCNH2ALDH1A1POLB | |
| SCHEMBL27795463 | 0.72 | CHRM2 (0.54) | CHRM2CHRM1KCNH2ALDH1A1SLC6A3 | |
| SCHEMBL10857299 | 0.63 | SYK (0.45) | ALDH1A1LMNACYP3A4 | |
| SCHEMBL21742010 | 0.61 | SMN1; SMN2 (0.46) | CHRM2CHRM1KCNH2ALDH1A1HRH1 | |
| SCHEMBL31292082 | 0.61 | NAMPT (0.39) | CYP19A1MAPK1TSHRCYP3A4 | |
| SCHEMBL17420592 | 0.61 | MAPK1 (0.40) | CYP19A1MAPK1ALDH1A1POLBTSHR | |
| SCHEMBL4266127 | 0.60 | CYP19A1 (0.55) | CYP19A1CYP3A4 | |
| SCHEMBL8356285 | 0.59 | ALDH1A1 (0.33) | CHRM2CHRM1ALDH1A1LMNA | |
| SCHEMBL29857708 | 0.59 | CYP19A1 (0.42) | CYP19A1GPR119CYP3A4 | |
| SCHEMBL12224821 | 0.59 | CYP19A1 (0.46) | CYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1188471-A | 1,4-disubstituted piepridine derivatives | BANYU PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |