Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptophan SCHEMBL4261643 | 0.96 | KDM4E (0.67) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27901971 | 0.92 | KDM4E (0.61) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL28827035 | 0.90 | KDM4E (0.64) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL3497602 | 0.89 | KDM4E (0.68) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27480942 | 0.89 | KMT2A (0.68) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL26977255 | 0.89 | KMT2A (0.57) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL6146838 | 0.88 | KMT2A (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL1487570 | 0.88 | KMT2A (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL11217425 | 0.88 | KDM4E (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL537138 | 0.88 | KDM4E (0.80) | KDM4EMAPTKMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151761-A | Subtilisin BPN' variants with reduced adsorption and increased hydrolysis | PROCTER & GAMBLE (US) | 1997-06-11 | — | — | CN | disclosed |