SCHEMBL27482175

SCHEMBL27482175

CCCCCCCCCCCCCCC1=CCCC1=O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.46
BACE1 P56817 1/20 0.46
PTGS2 P35354 6/20 0.40
ALOX5 P09917 4/20 0.40
PTPN1 P18031 1/20 0.40
GLS2 Q9UI32 1/20 0.40
GPR84 Q9NQS5 10/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11543697 1.00 ACHE (0.46) ACHEBACE1PTGS2ALOX5PTPN1
SCHEMBL243893 1.00 ACHE (0.46) ACHEBACE1PTGS2ALOX5PTPN1
SCHEMBL6896832 1.00 ACHE (0.46) ACHEBACE1PTGS2ALOX5PTPN1
SCHEMBL6903485 1.00 ACHE (0.46) ACHEBACE1PTGS2ALOX5PTPN1
SCHEMBL6901931 1.00 ACHE (0.46) ACHEBACE1PTGS2ALOX5PTPN1
SCHEMBL6898154 1.00 ACHE (0.46) ACHEBACE1PTGS2ALOX5PTPN1
SCHEMBL357488 0.98 ACHE (0.43) ACHEBACE1PTGS2ALOX5PTPN1
SCHEMBL1150883 0.92 ACHE (0.36) ACHEBACE1PTGS2ALOX5PTPN1
Cyclopentanone SCHEMBL28849888 0.92 ACHE (0.40) ACHEBACE1PTGS2ALOX5PTPN1
Acetic Acid SCHEMBL9004840 0.90 GAA (0.39) ACHEBACE1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1156432-C Cyclopentenone derivatives ������������ʽ���� 2004-07-07 CN disclosed
CN-1247528-A Cyclopentenone derivatives TAKARA SHUZO CO (JP) 2000-03-15 CN disclosed