SCHEMBL1150883

SCHEMBL1150883

CCCCC1=CCCC1=O

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
BACE1 P56817 1/20 0.36
DAO P14920 1/20 0.36
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
HTT P42858 2/20 0.33
GAA P10253 1/20 0.33
GSTP1 P09211 2/20 0.33
ALOX5 P09917 5/20 0.33
PTGS2 P35354 5/20 0.33
PTPN1 P18031 1/20 0.32
GLS2 Q9UI32 1/20 0.32
BRD9 Q9H8M2 1/20 0.32
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL357488 0.94 ACHE (0.43) ACHEBACE1HTTGAAALOX5
SCHEMBL6901931 0.92 ACHE (0.46) ACHEBACE1ALOX5PTGS2PTPN1
SCHEMBL6898154 0.92 ACHE (0.46) ACHEBACE1ALOX5PTGS2PTPN1
SCHEMBL11543697 0.92 ACHE (0.46) ACHEBACE1ALOX5PTGS2PTPN1
SCHEMBL6896832 0.92 ACHE (0.46) ACHEBACE1ALOX5PTGS2PTPN1
SCHEMBL27482175 0.92 ACHE (0.46) ACHEBACE1ALOX5PTGS2PTPN1
SCHEMBL6903485 0.92 ACHE (0.46) ACHEBACE1ALOX5PTGS2PTPN1
SCHEMBL243893 0.92 ACHE (0.46) ACHEBACE1ALOX5PTGS2PTPN1
SCHEMBL1238429 0.88 GSTP1 (0.44) ACHEBACE1DAOKDM4EPKM
SCHEMBL1044406 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229852-A Navel orange essential oil and extraction method thereof 郑州轻工业大学 2023-12-15 CN claimed
US-20240409486-A1 COMPOUND PRODUCING METHOD INCLUDING STEP OF ISOMERIZING ALPHA, BETA-UNSATURATED KETONE KAO CORPORATION (JP) 2024-12-12 US disclosed
CN-118103345-A Method for producing compound comprising isomerization step of alpha, beta-unsaturated ketone 花王株式会社 2024-05-28 CN disclosed
CN-117229852-A Navel orange essential oil and extraction method thereof 郑州轻工业大学 2023-12-15 CN disclosed
WO-2023144167-A1 NOVEL COMPOSITIONS FOR THE SUSTAINABLE CATALYSIS OF ORGANIC SYNTHESIS REACTIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-08-03 WO disclosed
EP-4215267-A1 NOVEL COMPOSITIONS FOR THE SUSTAINABLE CATALYSIS OF ORGANIC SYNTHESIS REACTIONS Centre national de la recherche scientifique (FR) 2023-07-26 EP disclosed
EP-4185621-A1 PROCESS FOR THE PREPARATION OF A MULTIMODAL POLYETHYLENE Borealis AG (AT) 2023-05-31 EP disclosed
EP-4185622-A1 METALLOCENE COMPLEXES AND CATALYSTS MADE THEREFROM Borealis AG (AT) 2023-05-31 EP disclosed
WO-2023063030-A1 COMPOUND PRODUCING METHOD INCLUDING STEP FOR ISOMERIZING α,β-UNSATURATED KETONE 花王株式会社 2023-04-20 WO disclosed
WO-2022018290-A1 PROCESS FOR THE PREPARATION OF A MULTIMODAL POLYETHYLENE BOREALIS AG (AT) 2022-01-27 WO disclosed
CN-1817837-B Carbonyl compound and method for preparing the same SUMITOMO CHEMICAL CO 2010-06-16 CN disclosed
CN-100357303-C Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer using the same SUMITOMO CHEMICAL CO (JP) 2007-12-26 CN disclosed
CN-1817837-A Substituted cyclopentadiene and method for producing the same SUMITOMO CHEMICAL CO (JP) 2006-08-16 CN disclosed
CN-1578783-A Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer using the same SUMITOMO CHEMICAL CO (JP) 2005-02-09 CN disclosed
US-6833481-B2 Catalytic dehydrative isomerization TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-12-21 US disclosed
US-20030109755-A1 Process for producing 2-alkyl-2cyclopentenones TAKASAGO INTERNATIONAL CORPORATION 2003-06-12 US disclosed
EP-1316541-A1 Process for producing 2-alkyl-2-cyclopentenones Takasago International Corporation (JP) 2003-06-04 EP disclosed
CN-1421429-A Process for producing 2-alkyl-2-cyclopentenone TAKASAGO PERFUMERY CO LTD (JP) 2003-06-04 CN disclosed
US-5116869-A Antitumor Agents, Bone Formation Accelerator TEIJIN LIMITED (JP) 1992-05-26 US disclosed
US-3953514-A Process for preparing cyclopentenone derivatives UBE INDUSTRIES, LTD. (JA) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409486-A1 COMPOUND PRODUCING METHOD INCLUDING STEP OF ISOMERIZING ALPHA, BETA-UNSATURATED KETONE CBR1, AKR1B1, AKR1C1 ACHE 3049/4885BACE1 743/4885DAO 2139/4885
US-20030109755-A1 Process for producing 2-alkyl-2cyclopentenones HSD3B2, DHPS, HSD3B1 ACHE 4748/4885BACE1 4376/4885DAO 2558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.