Methacrylic Acid

Methacrylic Acid

SCHEMBL27482178

C=C(C)C(=O)O.C=CC(=O)NOCCCC.C=CC(=O)O.C=CC(=O)O

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
HPGD P15428 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 1/20 0.36
HCAR2 Q8TDS4 3/20 0.36
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ALDH1A1 P00352 2/20 0.34
EPHX2 P34913 1/20 0.33
ATM Q13315 1/20 0.33
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CNR2 P34972 2/20 0.32
TRPV1 Q8NER1 2/20 0.32
THRB P10828 2/20 0.32
THRA P10827 1/20 0.32
S1PR1 P21453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27482177 0.90 TSHR (0.45) TSHRHPGDZDHHC20ZDHHC2ALOX15
SCHEMBL27609273 0.88 TSHR (0.43) TSHRHPGDZDHHC20ZDHHC2HCAR2
SCHEMBL194102 0.87 TSHR (0.52) TSHRHPGDZDHHC20ZDHHC2HCAR2
SCHEMBL28110146 0.82 ZDHHC20 (0.52) TSHRHPGDZDHHC20ZDHHC2HCAR2
Methacrylic Acid SCHEMBL27468315 0.81 ZDHHC20 (0.45) TSHRHPGDZDHHC20ZDHHC2ALOX15
SCHEMBL27872959 0.80 ZDHHC20 (0.55) TSHRHPGDZDHHC20ZDHHC2HCAR2
Methacrylic Acid SCHEMBL11308304 0.76 TSHR (0.73) TSHRHPGDHSD17B10HCAR2MAPT
SCHEMBL176017 0.76
Decane SCHEMBL5191634 0.76 TSHR (0.47) TSHRZDHHC20ZDHHC2ALOX15HSD17B10
Pentadecane SCHEMBL5191641 0.76 TSHR (0.47) TSHRZDHHC20ZDHHC2ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1188476-C Extinction electrolytic-deposition coating composition HIPPON PAINT CO LTD (JP) 2005-02-09 CN disclosed
CN-1169448-A Extinction electrolytic-deposition coating composition HIPPON PAINT CO LTD (JP) 1998-01-07 CN disclosed