Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.52 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27872959 | 0.98 | ZDHHC20 (0.55) | ZDHHC20ZDHHC2TSHRHPGDCNR2 | |
| SCHEMBL194102 | 0.94 | TSHR (0.52) | ZDHHC20ZDHHC2TSHRHPGDCNR2 | |
| SCHEMBL176017 | 0.86 | — | — | |
| SCHEMBL27609273 | 0.84 | TSHR (0.43) | ZDHHC20ZDHHC2TSHRHPGDCNR2 | |
| Methacrylic Acid SCHEMBL27482178 | 0.82 | TSHR (0.41) | ZDHHC20ZDHHC2TSHRHPGDCNR2 | |
| SCHEMBL27578764 | 0.80 | ALDH1A1 (0.36) | TSHRMAPT | |
| Methacrylic Acid SCHEMBL27482177 | 0.78 | TSHR (0.45) | ZDHHC20ZDHHC2TSHRHPGDCNR2 | |
| SCHEMBL27425076 | 0.78 | ACHE (0.39) | ZDHHC20ZDHHC2TSHRHPGDMAPT | |
| SCHEMBL27570362 | 0.78 | TSHR (0.38) | ZDHHC20ZDHHC2TSHRHPGD | |
| SCHEMBL27549948 | 0.78 | BBOX1 (0.40) | ZDHHC20ZDHHC2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108640861-A | \" one kettle way \" that alkynyl amide mediates prepares macrolide | 江西师范大学 | 2018-10-12 | — | — | CN | claimed |
| CN-108640861-A | \" one kettle way \" that alkynyl amide mediates prepares macrolide | 江西师范大学 | 2018-10-12 | — | — | CN | disclosed |
| CN-105294476-B | The synthetic method of 2 acyloxy acrylamides | 上海大学 | 2017-12-19 | — | — | CN | disclosed |
| CN-105294476-B | The synthetic method of 2 acyloxy acrylamides | 上海大学 | 2017-12-19 | — | — | CN | disclosed |
| CN-106146359-B | Mild and efficient preparation method of alpha-acyloxy alkenyl amide compound and application of alpha-acyloxy alkenyl amide compound in amide and polypeptide synthesis | 江西师范大学 | 2017-11-24 | — | — | CN | disclosed |
| CN-106146359-A | Mild and efficient preparation method of alpha-acyloxy alkenyl amide compound and application of alpha-acyloxy alkenyl amide compound in amide and polypeptide synthesis | 江西师范大学 | 2016-11-23 | — | — | CN | disclosed |