SCHEMBL2748246

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2748331	0.90	EGFR (0.57)	EGFRERBB2ERBB3ERBB4
	SCHEMBL2748353	0.85	EGFR (0.59)	EGFRERBB2ERBB3ERBB4
	SCHEMBL2748899	0.85	EGFR (0.67)	EGFRERBB2
	SCHEMBL2748791	0.85	EGFR (0.69)	EGFRERBB2MEN1KMT2ACYP3A4
	SCHEMBL2749768	0.84	EGFR (0.61)	EGFRERBB2ERBB3ERBB4
	SCHEMBL8367168	0.81	EGFR (0.89)	EGFRERBB2MEN1KMT2ACYP3A4
	SCHEMBL8366002	0.81	EGFR (1.00)	EGFRERBB2MEN1KMT2ACYP3A4
	SCHEMBL2747754	0.81	EGFR (0.48)	EGFRERBB2MEN1KMT2ACYP3A4
	SCHEMBL14090716	0.81	EGFR (0.79)	EGFRERBB2MEN1KMT2ACYP3A4
	SCHEMBL2750507	0.79	EGFR (0.54)	EGFRERBB2ERBB3ERBB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.