SCHEMBL27482575

SCHEMBL27482575

CCCCCCCCCCCCCCCCCCNc1cc(C)cc(C)c1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.50
THRB P10828 1/20 0.50
ABL1 P00519 1/20 0.49
DNM2 P50570 3/20 0.42
GPR84 Q9NQS5 8/20 0.42
MAPT P10636 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PLK1 P53350 3/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27520329 1.00 ADRA2A (0.50) ADRA2ATHRBABL1DNM2GPR84
SCHEMBL5605010 1.00 ADRA2A (0.50) ADRA2ATHRBABL1DNM2GPR84
SCHEMBL10381587 1.00 ADRA2A (0.50) ADRA2ATHRBABL1DNM2GPR84
SCHEMBL27893435 1.00 ADRA2A (0.50) ADRA2ATHRBABL1DNM2GPR84
SCHEMBL7998280 1.00 ADRA2A (0.50) ADRA2ATHRBABL1DNM2GPR84
Hydrochloric Acid SCHEMBL27500951 0.98 ADRA2A (0.49) ADRA2ATHRBABL1DNM2GPR84
Iodide SCHEMBL27772286 0.98 ADRA2A (0.49) ADRA2ATHRBABL1DNM2GPR84
Water SCHEMBL27432682 0.98 THRB (0.53) ADRA2ATHRBABL1DNM2GPR84
Bromide SCHEMBL27772305 0.98 ADRA2A (0.49) ADRA2ATHRBABL1DNM2GPR84
Iodide SCHEMBL27793343 0.98 ADRA2A (0.49) ADRA2ATHRBABL1DNM2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103251512-A Ester compounds for use in personal care products LUBRIZOL ADVANCED MAT INC 2013-08-21 CN disclosed
CN-102088949-B Ester Compounds for Personal Care Products LUBRIZOL ADVANCED MAT INC 2013-05-01 CN disclosed
CN-101448486-B Composition for inactivating enveloped viruses VIROBLOCK S A 2012-10-31 CN disclosed
CN-102416176-A Stabile isotonic lyophilized protein formulation GENENTECH INC 2012-04-18 CN disclosed
CN-101172099-B stable isotonic lyophilized protein formulation GENENTECH, INC. (US) 2012-02-15 CN disclosed
CN-102088949-A Ester Compounds for Personal Care Products LUBRIZOL ADVANCED MAT INC 2011-06-08 CN disclosed
CN-101056615-B Ophthalmic oil-in-water emulsions having a stable positive zeta potential NOVAGALI PHARMA SA 2011-05-11 CN disclosed
CN-101448486-A Composition for inactivating enveloped viruses VIROBLOCK S A (CH) 2009-06-03 CN disclosed
CN-101257923-A Anti-ccr7 receptor antibodies for the treatment of cancer UNIV MADRID AUTONOMA (ES) 2008-09-03 CN disclosed
CN-101252949-A Promotion of epithelial regeneration RENOVO LTD (GB) 2008-08-27 CN disclosed
CN-100360184-C Stable isotonic lyophilized protein formulation GENENTECH INC (US) 2008-01-09 CN disclosed
CN-101056615-A Ophthalmic oil-in-water emulsions having a stable positive zeta potential NOVAGALI PHARMA SA (FR) 2007-10-17 CN disclosed
CN-1223525-C Cleaning method RECKITT BENCKISER UK LTD (GB) 2005-10-19 CN disclosed
CN-1200676-C Method of reducing colour loss from dyed hair using organic amino compounds UNILEVER NV (NL) 2005-05-11 CN disclosed
CN-1585607-A Food washing composition JOHNSON DIVERSEY INC (US) 2005-02-23 CN disclosed
CN-1539505-A Stable isotonic lyophilized protein formulation �����ɷ� 2004-10-27 CN disclosed
CN-1151842-C Stable isotonic lyophilized protein formulations �����ɷ� 2004-06-02 CN disclosed
CN-1450979-A Cleaning method RECKITT BENCKISER UK LTD (GB) 2003-10-22 CN disclosed
CN-1364074-A Method of reducing colour loss from dyed hair using organic amino compounds UNILEVER NV (NL) 2002-08-14 CN disclosed
CN-1191490-A Stable isotonic lyophilized protein formulations GENENTECH INC (US) 1998-08-26 CN disclosed