Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498857 | 0.90 | ALDH1A1 (0.45) | MEN1KMT2ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL6978355 | 0.86 | GFER (0.55) | GFERMEN1KMT2AHTR7TSHR | |
| SCHEMBL6978349 | 0.86 | GFER (0.55) | GFERMEN1KMT2AHTR7TSHR | |
| SCHEMBL6978386 | 0.75 | KMT2A (0.49) | GFERMEN1KMT2AHTR7TSHR | |
| SCHEMBL6978390 | 0.75 | KMT2A (0.49) | GFERMEN1KMT2AHTR7TSHR | |
| SCHEMBL1376551 | 0.75 | KMT2A (0.53) | MEN1KMT2AHTR7TSHRMAPT | |
| SCHEMBL1375794 | 0.75 | KMT2A (0.53) | MEN1KMT2AHTR7TSHRMAPT | |
| SCHEMBL6981156 | 0.71 | DRD3 (0.44) | GFERHTR7MAPTNPSR1ALDH1A1 | |
| SCHEMBL2165481 | 0.70 | ALDH1A1 (0.67) | MEN1KMT2ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL6978571 | 0.70 | KMT2A (0.44) | MEN1KMT2AHTR7TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1195343-A | Piperazine derivatives and use of same | SENJU PHARMA CO (JP) | 1998-10-07 | — | — | CN | disclosed |
| CN-1163145-A | Inhibiting agent for vascular formation | SENJI SEIYAKU K K (JP) | 1997-10-29 | — | — | CN | disclosed |