SCHEMBL27484110

SCHEMBL27484110

COc1cccc(C(C)C(=O)OC(C)=O)c1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
MTNR1A P48039 5/20 0.47
MTNR1B P49286 5/20 0.47
POLB P06746 1/20 0.46
PTGS2 P35354 4/20 0.46
AKR1C3 P42330 3/20 0.45
AKR1C2 P52895 3/20 0.45
CDC42 P60953 1/20 0.45
RAC1 P63000 1/20 0.45
CYP1A2 P05177 1/20 0.45
TSHR P16473 1/20 0.45
SLC22A6 Q4U2R8 1/20 0.45
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5352751 0.85 PTGS1 (0.60) PTGS1L3MBTL1TDP1MTNR1AMTNR1B
SCHEMBL27776915 0.85 PTGS1 (0.70) PTGS1PTGS2AKR1C3
SCHEMBL16800683 0.83 PTGS1 (0.58) PTGS1L3MBTL1MTNR1AMTNR1BPOLB
SCHEMBL10633957 0.83 TDP1 (0.71) PTGS1L3MBTL1TDP1PTGS2AKR1C3
SCHEMBL4694517 0.83 TDP1 (0.71) PTGS1L3MBTL1TDP1PTGS2AKR1C3
SCHEMBL27606784 0.82 PTGS1 (0.56) PTGS1L3MBTL1MTNR1AMTNR1BPOLB
SCHEMBL28121831 0.81 PTGS1 (0.56) PTGS1L3MBTL1TDP1MTNR1AMTNR1B
SCHEMBL3918115 0.81 L3MBTL1 (0.55) PTGS1L3MBTL1TDP1MTNR1AMTNR1B
SCHEMBL27476524 0.81 LMNA (0.46) PTGS1PTGS2AKR1C3AKR1C2SLC22A6
SCHEMBL10958940 0.81 KDM4E (0.53) PTGS1L3MBTL1TDP1MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104531785-A Method for catalytically synthesizing ethyl (R)-4-aryl-3-hydroxybutyrate by utilizing potato whole cell UNIV JIANGNAN 2015-04-22 CN disclosed
CN-1204328-A 1, 3-oxazin-4-one derivatives as herbicides RHONE POULENC AGRICULTURE (GB) 1999-01-06 CN disclosed
CN-1201790-A Herbicide MITSUBISHI CHEM CORP (JP) 1998-12-16 CN disclosed