SCHEMBL27484155

SCHEMBL27484155

Cc1c(F)c(O)c(F)c([N+](=O)[O-])c1F

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.36
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
S100A4 P26447 1/20 0.34
GRIN2D O15399 4/20 0.33
GRIN3B O60391 4/20 0.33
GRIN1 Q05586 4/20 0.33
GRIN2A Q12879 4/20 0.33
GRIN2B Q13224 4/20 0.33
GRIN2C Q14957 4/20 0.33
GRIN3A Q8TCU5 4/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
IMPDH2 P12268 1/20 0.32
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14359869 0.84 TDP1 (0.41) ALDH1A1TDP1GRIN2DGRIN3BGRIN1
SCHEMBL10566686 0.83 GPR35 (0.36) GPR35ALDH1A1TDP1S100A4GRIN2D
SCHEMBL27718348 0.83 GPR35 (0.36) GPR35ALDH1A1TDP1S100A4GRIN2D
SCHEMBL28089648 0.83 GPR35 (0.36) GPR35ALDH1A1TDP1S100A4GRIN2D
SCHEMBL8306891 0.83 GPR35 (0.36) GPR35ALDH1A1TDP1S100A4GRIN2D
SCHEMBL27491841 0.83 GPR35 (0.36) GPR35ALDH1A1TDP1S100A4GRIN2D
SCHEMBL25355025 0.80 S100A4 (0.38) GPR35S100A4GRIN2DGRIN3BGRIN1
SCHEMBL10976267 0.80 TDP1 (0.38) ALDH1A1TDP1GRIN2DGRIN3BGRIN1
SCHEMBL29150526 0.80 TDP1 (0.41) ALDH1A1TDP1GRIN2DGRIN3BGRIN1
SCHEMBL17468410 0.80 TDP1 (0.41) ALDH1A1TDP1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1184123-A Organic optical component MITSUI TOATSU CHEMICALS (JP) 1998-06-10 CN disclosed