Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509308 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP2C19NPSR1MAPTAAK1 | |
| SCHEMBL14290430 | 0.71 | PBRM1 (0.37) | MAPTADRA2A | |
| SCHEMBL14107049 | 0.70 | TDP1 (0.57) | CYP1A2CYP2C19NPSR1MAPTAAK1 | |
| SCHEMBL17417902 | 0.69 | CYP1A2 (0.55) | CYP1A2CYP2C19NPSR1MAPTAAK1 | |
| SCHEMBL2249683 | 0.69 | CYP1A2 (0.69) | CYP1A2CYP2C19NPSR1MAPTAAK1 | |
| SCHEMBL10847076 | 0.68 | CYP1A2 (0.58) | CYP1A2CYP2C19NPSR1MAPTAAK1 | |
| SCHEMBL2246315 | 0.68 | CYP1A2 (0.54) | CYP1A2CYP2C19NPSR1MAPTHTR2C | |
| SCHEMBL10361404 | 0.68 | NR3C1 (0.49) | CYP1A2CYP2C19NPSR1MAPTAAK1 | |
| SCHEMBL30780909 | 0.67 | CYP1A2 (0.53) | CYP1A2CYP2C19NPSR1MAPTAAK1 | |
| SCHEMBL8411387 | 0.67 | CYP1A2 (0.56) | CYP1A2CYP2C19NPSR1MAPTAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1165303-C | DNA-binding indole derivatives, prodrugs and immunoconjugates thereof as antitumor agents | 全景研究有限公司 | 2004-09-08 | — | — | CN | disclosed |