Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 4/20 | 0.35 |
| ▸ | PNMT | P11086 | 8/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28699917 | 0.76 | TYR (0.36) | LMNAMAPT | |
| SCHEMBL6209606 | 0.74 | MAOB (0.41) | CA2AR | |
| SCHEMBL8864150 | 0.73 | ESR1 (0.36) | PBRM1AHRPNMTADRA2AADRA2B | |
| SCHEMBL18114486 | 0.73 | PBRM1 (0.56) | PBRM1AHRPNMTADRA2AADRA2B | |
| SCHEMBL27651808 | 0.73 | MAOB (0.41) | CA2AR | |
| SCHEMBL13296078 | 0.71 | SMN1; SMN2 (0.45) | PBRM1AHRPNMTBLM | |
| SCHEMBL30664932 | 0.71 | SMN1; SMN2 (0.45) | PBRM1AHRPNMTBLM | |
| SCHEMBL27485696 | 0.71 | CYP1A2 (0.49) | ADRA2AMAPT | |
| SCHEMBL13903616 | 0.70 | GLS (0.40) | PBRM1MAPTHTT | |
| SCHEMBL28204525 | 0.70 | BRD4 (0.34) | PBRM1AHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335908-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONISTS | LILLY CO ELI (US) | 2008-02-13 | — | — | EP | disclosed |