SCHEMBL27486181

SCHEMBL27486181

CCCON1C(C)(C)CC(NCCCCCCN)CC1(C)C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SQLE Q14534 1/20 0.35
GNAI3 P08754 2/20 0.33
GNAO1 P09471 2/20 0.33
GNAI1 P63096 2/20 0.33
SLC2A1 P11166 1/20 0.32
S1PR4 O95977 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31
GBA1 P04062 1/20 0.31
GLB1 P16278 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893039 0.93 GNAI3 (0.37) GNAI3GNAO1GNAI1SLC2A1S1PR4
SCHEMBL893205 0.86 GNAI3 (0.33) GNAI3GNAO1GNAI1S1PR4S1PR1
SCHEMBL8532351 0.84 GNAI3 (0.41) GNAI3GNAO1GNAI1SLC2A1S1PR4
SCHEMBL26668878 0.84 GNAI3 (0.41) GNAI3GNAO1GNAI1SLC2A1S1PR4
SCHEMBL9491106 0.84 GNAI3 (0.41) GNAI3GNAO1GNAI1SLC2A1S1PR4
SCHEMBL12910969 0.81 ALDH1A1 (0.31) GNAI3GNAO1GNAI1
SCHEMBL870983 0.81 GNAI3 (0.38) GNAI3GNAO1GNAI1SLC2A1S1PR4
SCHEMBL18872779 0.80
SCHEMBL12517417 0.80 GNAI3 (0.35) GNAI3GNAO1GNAI1SLC2A1S1PR4
SCHEMBL17928926 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100384826-C Preparation of sterically hindered amine ethers CIBA SC HOLDING AG (CH) 2008-04-30 CN disclosed
CN-1202085-C Preparation of sterically hindered amine ethers CIBA SC HOLDING AG (CH) 2005-05-18 CN disclosed
CN-1552758-A Preparation of sterically hindered amine ethers 西巴特殊化学品控股有限公司 2004-12-08 CN disclosed