Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.49 |
| ▸ | ITGAV | P06756 | 15/20 | 0.49 |
| ▸ | ITGB6 | P18564 | 12/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.49 |
| ▸ | ITGB8 | P26012 | 3/20 | 0.49 |
| ▸ | ITGA8 | P53708 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345759 | 0.89 | ITGB3 (0.56) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL27486479 | 0.89 | ITGB3 (0.39) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL27503087 | 0.88 | GPR139 (0.41) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7834703 | 0.87 | ITGB3 (0.48) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7340958 | 0.83 | ITGB3 (0.70) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL6773894 | 0.82 | ITGB3 (0.47) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7836172 | 0.82 | GPR139 (0.39) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7345743 | 0.81 | GPR139 (0.41) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7838278 | 0.80 | ITGB3 (0.56) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL7340345 | 0.80 | TP53 (0.39) | ITGB3ITGAVITGB1ITGA5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | claimed |