SCHEMBL27486243

SCHEMBL27486243

NC(=O)N(N)c1cc(F)cc(N(N)C(N)=O)c1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
PARP1 P09874 2/20 0.33
ERN1 O75460 1/20 0.33
KCNN4 O15554 2/20 0.31
ALDH1A1 P00352 1/20 0.30
HCAR1 Q9BXC0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6486260 0.79 PARP1 (0.50) CES2CES1PARP1KCNN4ALDH1A1
SCHEMBL28084122 0.78
Hydrochloric Acid SCHEMBL27984190 0.77 CA12 (0.31) PARP1
SCHEMBL27386917 0.77
SCHEMBL28094995 0.77 TPMT (0.34) PARP1ALDH1A1HCAR1
SCHEMBL27485584 0.77 CES2 (0.42) CES2CES1ALDH1A1
SCHEMBL27524279 0.76 CA12 (0.39) ALDH1A1HCAR1
SCHEMBL28135524 0.74 MEN1 (0.41) PARP1ALDH1A1
SCHEMBL27911537 0.74 ACHE (0.34)
SCHEMBL7909962 0.73 TPMT (0.39) PARP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104093390-B Oxide hair dye SHISEIDO CO.,LTD. (JP) 2016-02-17 CN disclosed
CN-103108621-B Oxidation hair dye composition SHISEIDO CO.,LTD. (JP) 2016-01-06 CN disclosed
CN-104093390-A Oxidation hair dye SHISEDO CO LTD 2014-10-08 CN disclosed
CN-103108621-A Oxidation hair dye composition SHISEIDO CO LTD 2013-05-15 CN disclosed
CN-100374101-C Hair dye composition SHISEIDO CO LTD (JP) 2008-03-12 CN disclosed
CN-1201718-C Hair dyeing composition KAO CORP (JP) 2005-05-18 CN disclosed
CN-1541642-A Hair dye composition 株式会社资生堂 2004-11-03 CN disclosed
CN-1297734-A Hair dyeing composition KAO CORP (JP) 2001-06-06 CN disclosed
CN-1231171-A Two-agent mixing type cosmetics SHISEIDO CO LTD (JP) 1999-10-13 CN disclosed