Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 18/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936758 | 0.81 | SLC6A4 (0.40) | TRPA1TSHRSLC6A3HSD11B1 | |
| SCHEMBL5160386 | 0.67 | OPRM1 (0.44) | SLC6A3HSD11B1 | |
| SCHEMBL6939057 | 0.65 | SLC6A4 (0.42) | TRPA1SLC6A3HSD11B1 | |
| SCHEMBL6939750 | 0.65 | TSHR (0.42) | TSHRHSD11B1 | |
| SCHEMBL5163207 | 0.64 | OPRM1 (0.44) | SLC6A3 | |
| SCHEMBL5159940 | 0.64 | OPRM1 (0.40) | TSHRSLC6A3 | |
| SCHEMBL5158046 | 0.63 | OPRM1 (0.43) | TRPA1TSHRSLC6A3 | |
| SCHEMBL6938861 | 0.62 | GRIN2B (0.39) | TRPA1 | |
| SCHEMBL5158611 | 0.62 | OPRM1 (0.41) | TRPA1SLC6A3 | |
| SCHEMBL7732583 | 0.61 | OPRM1 (0.38) | TSHRSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1183098-C | 3-amino-3-aryl-1-alcohol derivatives and preparation and use thereof | — | 2005-01-05 | — | — | CN | claimed |
| CN-1270162-A | 3-amino-3-aryl-1-alcohol derivatives and preparation and use thereof | GRUENENTHAL GMBH (DE) | 2000-10-18 | — | — | CN | claimed |
| CN-1183098-C | 3-amino-3-aryl-1-alcohol derivatives and preparation and use thereof | — | 2005-01-05 | — | — | CN | disclosed |
| CN-1270162-A | 3-amino-3-aryl-1-alcohol derivatives and preparation and use thereof | GRUENENTHAL GMBH (DE) | 2000-10-18 | — | — | CN | disclosed |