Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30904497 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2PDPK1PDE10A | |
| SCHEMBL30521262 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2PDPK1PDE10A | |
| SCHEMBL30829728 | 0.81 | SMN1; SMN2 (0.62) | ALDH1A1LMNASMN1; SMN2PDPK1PDE10A | |
| SCHEMBL30231203 | 0.81 | SMN1; SMN2 (0.58) | ALDH1A1LMNASMN1; SMN2PDPK1PDE10A | |
| SCHEMBL28902805 | 0.81 | SMN1; SMN2 (0.58) | ALDH1A1LMNASMN1; SMN2PDPK1PDE10A | |
| SCHEMBL24425191 | 0.81 | SMN1; SMN2 (0.62) | ALDH1A1LMNASMN1; SMN2PDPK1PDE10A | |
| SCHEMBL31389818 | 0.81 | SMN1; SMN2 (0.58) | ALDH1A1LMNASMN1; SMN2PDPK1PDE10A | |
| SCHEMBL34471393 | 0.81 | LMNA (0.58) | ALDH1A1LMNASMN1; SMN2PDPK1PDE10A | |
| SCHEMBL21712337 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2PDPK1PDE10A | |
| SCHEMBL6118333 | 0.80 | SMN1; SMN2 (0.59) | ALDH1A1LMNASMN1; SMN2PDPK1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037817-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2018-02-08 | — | — | US | disclosed |
| US-8178668-B2 | 2-aminopyridine kinase inhibitors | OSI Pharmaceuticals, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| EP-2265270-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | OSI Pharmaceuticals, Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009099982-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
| US-20090197862-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | OSI PHARMACEUTICALS, INC. | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197862-A1 | 2-AMINOPYRIDINE KINASE INHIBITORS | ERBB2, ABL2, TIE1 | ALDH1A1 945/4885LMNA 3582/4885SMN1; SMN2 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.